Extractables and Leachables (E&L) studies are often assigned to laboratory personnel trained in routine sample preparation, data collection and interpretation despite the complexity of investigation encountered with complex devices.
Preparation of sample extracts is a very important process for trace level analysis of unknown compounds in complex matrices. Preparation and analysis of sample extracts require profound knowledge of sample handling, chemistry, chromatography, spectroscopy, technical skills, dedicated laboratory environment and equipment, extensive training in data acquisition and interpretation. In addition, identification relying on search libraries or database may lead to misidentification, and quantification using relative response factor can swing the results by multiple factors either way.
This webinar will highlight critical issues facing not only analytical chemists but extractables and leachables concept, guidelines, toxicologists, consultants, manufacturers and suppliers.
It will provide scientific principles for optimization of data collection and interpretation for E&L investigations. After all, the data is as good as the one behind the machine, and a toxicological safety evaluation of any device, no matter how simple or complex it is, is as good as the data supporting it.